Idiopathic hyperzincemia with associated copper deficiency anemia: a diagnostic dilemma
نویسندگان
چکیده
Prompt serum copper and zinc in addition to vitamin B12 levels should be measured in patients suffering from refractory anemia with neurological symptoms. A timely copper supplementation can help revert the hematological and possibly the neurological manifestations.
منابع مشابه
Myelopolyneuropathy and pancytopenia due to copper deficiency and high zinc levels of unknown origin: further support for existence of a new zinc overload syndrome.
OBJECTIVE To describe a patient with idiopathic zinc overload without an identifiable source and secondary copper deficiency causing myelopolyneuropathy and pancytopenia. DESIGN Case report. PATIENT AND RESULTS A 46-year-old man presented with severe bone marrow suppression and subsequently developed progressive myelopathy with sensory ataxia. No identifiable cause of myelopathy was detecte...
متن کاملCopper deficiency myelopathy (human swayback).
The hematologic manifestations of copper deficiency are well known and include anemia and neutropenia. In the past few years, the neurological manifestations of acquired copper deficiency in humans has been recognized, the most common being a myelopathy presenting with a spastic gait and prominent sensory ataxia. The known causes of acquired copper deficiency include prior gastric surgery, exce...
متن کاملPancytopenia related to dental adhesive in a young patient.
Copper deficiency resulting in hypocupremia is a rare cause of pancytopenia associated with a neurological syndrome. Hypocupremia may also occur as a consequence of excessive oral zinc consumption as described by Brewer et al and several other groups. Dental fixatives have been described as a potential source of hyperzincemia in patients. Despite the recently modified dental fixatives with safe...
متن کاملThe prevalence of iron deficiency anemia in children with Attention- Deficit/ Hyperactivity Disorder in Tabriz
Abstract Background: Iron deficiency anemia (IDA (is raised as a major public health issue leading to an increased risk of child mortality and has a negative effect on cognition and physical development. It has been suggested as a possible cause of the Attention-deficit/ hyperactivity disorder (ADHD (. So we decided to estimate prevalence of iron deficiency anemia in children with this disorde...
متن کاملDenture cream: an unusual source of excess zinc, leading to hypocupremia and neurologic disease.
BACKGROUND Chronic, excess zinc intake can result in copper deficiency and profound neurologic disease. However, when hyperzincemia is identified, the source often remains elusive. We identified four patients, one previously reported, with various neurologic abnormalities in the setting of hypocupremia and hyperzincemia. Each of these patients wore dentures and used very large amounts of dentur...
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2015